patternschemav0.3.8

variantreference kind

Identified by
:variant/id global id
Attributes
36
Referenced by
1 attributes

Attributes

AttributeTypeCardinalityDescription
HGVSc
:variant/HGVSc
stringoneThe HGVSc string for this variant, see http://varnomen.hgvs.org/
HGVSp
:variant/HGVSp
stringmanyThe HGVSp strings for this variant, see http://varnomen.hgvs.org/
alt-allele
:variant/alt-allele
stringoneThe alternate allele for this variant
alt-allele-2
:variant/alt-allele-2
stringoneThe 2nd alternate allele for this variant
alt-amino-acid
:variant/alt-amino-acid
stringoneThe alternate one letter coded amino acid sequence for this variant (ie A, R)
classification
:variant/classification
variant.classificationoneThe classification of this variant, refers to idents in the 'variant.classification' namespace
context
:variant/context
stringoneThe reference allele per VCF specs, and its five flanking base pairs
coordinate-string
:variant/coordinate-string
stringoneThe coordinate string (summarized genomic coordinate info) for this variant.
cosmic
:variant/cosmic
stringmanyOverlapping COSMIC variants
dbSNP
:variant/dbSNP
stringmanyA list of dbSNP (https://www.ncbi.nlm.nih.gov/projects/SNP/) ids for this variant
exac-af
:variant/exac-af
stringoneGlobal allele frequency from ExAC, in range [0, 1]. See http://exac.broadinstitute.org/
exac-af-adj
:variant/exac-af-adj
floatoneAdjusted global allele frequency from ExAC, in range [0, 1]. See http://exac.broadinstitute.org/
exac-afr
:variant/exac-afr
floatoneAfrican/African-American allele frequency from ExAC, in range [0, 1]. See http://exac.broadinstitute.org/
exac-amr
:variant/exac-amr
floatoneAmerican allele frequency from ExAC, in range [0, 1]. See http://exac.broadinstitute.org/
exac-eas
:variant/exac-eas
floatoneEast Asian allele frequency from ExAC, in range [0, 1]. See http://exac.broadinstitute.org/
exac-fin
:variant/exac-fin
floatoneFinnish allele frequency from ExAC, in range [0, 1]. See http://exac.broadinstitute.org/
exac-nfe
:variant/exac-nfe
floatoneNon-Finnish European allele frequency from ExAC, in range [0, 1]. See http://exac.broadinstitute.org/
exac-oth
:variant/exac-oth
floatoneOther allele frequency from ExAC, in range [0, 1]. See http://exac.broadinstitute.org/
exac-sas
:variant/exac-sas
floatoneSouth Asian allele frequency from ExAC, in range [0, 1]. See http://exac.broadinstitute.org/
external-ids
:variant/external-ids
stringmanyA list of IDs which may appear in external databases, e.g. rs*, COS*, agnostic to a specific reference. Do not use this attribute if the identifier is not prefixed or its reference source is not otherwise discernible.
feature-type
:variant/feature-type
variant.featureoneThe type of feature (transcript, regulatory, motif), refers to idents in the 'variant.feature.type' namespace
gene
:variant/gene
geneoneThe gene for this variant
genomic-coordinates
:variant/genomic-coordinates
genomic-coordinateoneThe coordinates of this variant
id
:variant/id
stringoneunique identityGlobally unique id for this variant. This is constructed by joining using '/' the coordinates, ref-allele and alt-allele
impact
:variant/impact
variant.impactoneThe impact modifier for this variant. Refers to entities in the variant.impact namespace
max-af
:variant/max-af
floatoneMaximum reference allele frequency, as annotated by VEP or snpEff. This is a measurement of how prevalent the allele is in reference populations (therefore assumed non-lethal germline variant).
neo-antigens
:variant/neo-antigens
neo-antigenmanyThe list of neo-antigens associated with this variant
partner-genes
:variant/partner-genes
genemanyOther genes impacted by this variant, as in large deletions, fusions, and other structural re-arrangements.
partner-genomic-coordinates
:variant/partner-genomic-coordinates
genomic-coordinateoneOther coordinates impacted by a structural variant, e.g. novel fusion / breakend partners.
publication
:variant/publication
stringmanyDOI of publication associated with this variant, as a string
quick-summary
:variant/quick-summary
stringoneSummarized name for variant as [hgnc_symbol]-[HGSVp]
ref-allele
:variant/ref-allele
stringoneThe reference allele for this variant
ref-amino-acid
:variant/ref-amino-acid
stringoneThe reference one letter coded amino acid sequence for this variant (ie A, R)
so-consequences
:variant/so-consequences
so-sequence-featuremanyThe functional consequence of the variant, in sequence ontology terms (http://www.sequenceontology.org/). Refers to so-sequence-feature entities
structural-category
:variant/structural-category
variant.structural-categoryoneThe category (as enum) for this structural variant, in variant.structural-category namespace. All structural variants must have this attribute.
type
:variant/type
variant.typeoneThe type of this variant, refers to idents in the 'variant.type' namespace

Referenced by

AttributeOn kindCardinality
:measurement/variantmeasurementone