patternschemav0.3.8

clinical-observationkind

Parent
clinical-observation-set
Identified by
:clinical-observation/uid context id
Attributes
89
Referenced by
1 attributes

Attributes

AttributeTypeCardinalityDescription
abs-basophils
:clinical-observation/abs-basophils
doubleoneAbs Basophils, in x10E9/L. Source feed writes this as /nl or x10E9/L; equivalent notations, normalised on import.
abs-eosinophils
:clinical-observation/abs-eosinophils
doubleoneAbs Eosinophils, in x10E9/L. Source feed writes this as /nl or x10E9/L; equivalent notations, normalised on import.
abs-immature-granulocytes
:clinical-observation/abs-immature-granulocytes
doubleoneAbs Immature Granulocytes, in x10E9/L.
abs-lymphocytes
:clinical-observation/abs-lymphocytes
doubleoneAbs Lymphocytes, in x10E9/L. Source feed writes this as /nl or x10E9/L; equivalent notations, normalised on import.
abs-monocytes
:clinical-observation/abs-monocytes
doubleoneAbs Monocytes, in x10E9/L. Source feed writes this as /nl or x10E9/L; equivalent notations, normalised on import.
abs-neutrophils
:clinical-observation/abs-neutrophils
doubleoneAbs Neutrophils, in x10E9/L. Source feed writes this as /nl or x10E9/L; equivalent notations, normalised on import.
absolute-leukocyte-count
:clinical-observation/absolute-leukocyte-count
longoneThe absolute leukocyte count expressed in number of cells per microliter
absolute-monocyte-count
:clinical-observation/absolute-monocyte-count
longoneThe absolute monocyte count expressed in number of cells per microliter
albumin
:clinical-observation/albumin
doubleoneAlbumin, in g/dL.
alk-phos
:clinical-observation/alk-phos
doubleoneAlkaline phosphatase, in U/L.
alt
:clinical-observation/alt
doubleoneAlanine aminotransferase, in U/L.
anion-gap
:clinical-observation/anion-gap
doubleoneAnion gap, in mmol/L.
ast
:clinical-observation/ast
doubleoneAspartate aminotransferase, in U/L.
biopsy
:clinical-observation/biopsy
stringoneFreetext type of biopsy taken. Result can be stored in freetext-result
bmi
:clinical-observation/bmi
floatoneThe body mass index of the subject. Unless more information is available, such observations should be connected to the baseline timepoint
bor
:clinical-observation/bor
clinical-observation.boroneThe best overall response (RECIST) of the subject. Such observations should be connected to the End of Study (EOS) timepoint
bun
:clinical-observation/bun
doubleoneBlood urea nitrogen, in mg/dL.
ca19-9
:clinical-observation/ca19-9
floatoneCA19-9 (Cancer Antigen 19-9) measurement from blood, in U/mL
calcium
:clinical-observation/calcium
doubleoneCalcium, in mg/dL.
chloride
:clinical-observation/chloride
doubleoneChloride, in mmol/L.
co2
:clinical-observation/co2
doubleoneCarbon dioxide (bicarbonate), in mmol/L.
creatinine
:clinical-observation/creatinine
doubleoneCreatinine, in mg/dL.
ctc
:clinical-observation/ctc
floatoneCTC (Ciculating Tumor Cells) measurement from blood, in CTC/7.5 mL whole blood
dcb
:clinical-observation/dcb
booleanoneWhether this patient has experienced Durable Clinical Benefit. Such observations should be connected to the End of Study (EOS) timepoint
detection
:clinical-observation/detection
clinical-observation.detectiononeDetection status of the result: refers to enums in the clinical-observation.detection namespace -- detected, not-detected, below-loq.
dfi
:clinical-observation/dfi
floatoneThe length of time (in months) the length of time after primary treatment for a cancer ends that the patient survives without any signs or symptoms of that cancer. Such observations should be connected to the End of Study (EOS) timepoint
dfi-event
:clinical-observation/dfi-event
booleanoneIf DFI observation is censored (use false as the value) or connected to an event (use true)
dfi-reason
:clinical-observation/dfi-reason
clinical-observation.event-reasononeThe reason (e.g. progression, censoring etc.) supplied for clinical observation DFI. Refers to entities in the :clinical-observation.event-reason namespace. See https://candel.parkerici.org/schema/#representing-data-for-survival-analysis-eg-pfs-os-etc for more information about modeling survival data
disease-stage
:clinical-observation/disease-stage
clinical-observation.disease-stageoneThe stage of the disease. Refers to entities in the 'disease.stage' namespace. This is a clinical-observation in order to allow the possibility for re-staging (even though technically tumor stage is not a time-varying concept)
egfr
:clinical-observation/egfr
doubleoneEstimated glomerular filtration rate, in mL/min/1.73m2.
eosinophils
:clinical-observation/eosinophils
doubleoneEosinophils %, in %.
freetext-result
:clinical-observation/freetext-result
stringoneThe result generated from this clinical observation
glucose
:clinical-observation/glucose
doubleoneGlucose, in mg/dL.
hematocrit
:clinical-observation/hematocrit
doubleoneHematocrit, in %.
hemoglobin
:clinical-observation/hemoglobin
doubleoneHemoglobin, in g/dL.
id
:clinical-observation/id
stringoneThe id of the clinical observation. Must be unique within this dataset (but not within the entire database)
imaging
:clinical-observation/imaging
clinical-observation.imagingmanyThe type of imaging that was done for this clincal observation
imaging-site
:clinical-observation/imaging-site
stringmanyAnatomic site where imaging was performed
inr
:clinical-observation/inr
doubleoneInternational normalised ratio.
ir-recist
:clinical-observation/ir-recist
clinical-observation.ir-recistoneThe irRECIST (Immune Related Response Evaluation Critera in Solid Tumors) score for this observation, refers to idents in the 'ir.recist' namespace
lab-out-of-range
:clinical-observation/lab-out-of-range
booleanoneTrue when the reporting laboratory flagged this result outside its reference interval.
lab-reference-high
:clinical-observation/lab-reference-high
doubleoneUpper bound of the reporting laboratory's reference interval for this analyte.
lab-reference-low
:clinical-observation/lab-reference-low
doubleoneLower bound of the reporting laboratory's reference interval for this analyte. Lab- and method-specific, so it is stored per result rather than per analyte.
lab-test
:clinical-observation/lab-test
lab-testoneThe laboratory analyte this observation reports, for analytes outside the named common panels. Part of the clinical-observation composite id, so several analytes drawn the same day stay distinct entities.
lab-unit
:clinical-observation/lab-unit
stringoneUnit the lab reported this result in, verbatim from the source feed.
lab-value
:clinical-observation/lab-value
doubleoneNumeric result for the :clinical-observation/lab-test analyte, in :clinical-observation/lab-unit.
ldh
:clinical-observation/ldh
floatoneLactate Dehydrogenase (LDH) measurement in blood, expressed in U/L
lymphocytes
:clinical-observation/lymphocytes
doubleoneLymphocytes %, in %.
magnesium
:clinical-observation/magnesium
doubleoneMagnesium, in mg/dL.
mch
:clinical-observation/mch
doubleoneMean corpuscular hemoglobin, in pg.
mchc
:clinical-observation/mchc
doubleoneMean corpuscular hemoglobin concentration, in g/dL.
mcv
:clinical-observation/mcv
doubleoneMean corpuscular volume, in fL.
metastasis-gdc-anatomic-sites
:clinical-observation/metastasis-gdc-anatomic-sites
gdc-anatomic-sitemanyThe GDC anatomic site(s) at which metastasis have been observed
metastatic
:clinical-observation/metastatic
booleanoneIndicates that the disease has become metastatic
monocytes
:clinical-observation/monocytes
doubleoneMonocytes %, in %.
mpv
:clinical-observation/mpv
doubleoneMean platelet volume, in fL.
natera-signatera-mtm-per-ml
:clinical-observation/natera-signatera-mtm-per-ml
floatonectDNA fraction from Signatera in mtm/mL
neutrophils
:clinical-observation/neutrophils
doubleoneNeutrophils %, in %.
northstar-response-v2
:clinical-observation/northstar-response-v2
floatoneTumour-methylation response score from the BillionToOne Northstar Response v2 assay. Sits alongside the Signatera and Personalis ctDNA attributes; all three can be reported on the same day.
os
:clinical-observation/os
floatoneThe overall survival of the subject in months. Such observations should be connected to the End of Study (EOS) timepoint.
os-event
:clinical-observation/os-event
booleanoneIf OS observation is censored (use false as the value) or connected to an event (use true)
os-reason
:clinical-observation/os-reason
clinical-observation.event-reasononeThe reason (e.g. progression, censoring etc.) supplied for clinical observation OS. Refers to entities in the :clinical-observation.event-reason namespace. See https://candel.parkerici.org/schema/#representing-data-for-survival-analysis-eg-pfs-os-etc for more information about modeling survival data
personalis-nextpersonaldx-ctdnafraction-ppm
:clinical-observation/personalis-nextpersonaldx-ctdnafraction-ppm
floatonectDNA fraction from Personalis NeXT assay in PPM
pfs
:clinical-observation/pfs
floatoneThe progression free survival of the subject in months. Such observations should be connected to the End of Study (EOS) timepoint
pfs-event
:clinical-observation/pfs-event
booleanoneIf PFS observation is censored (use false as the value) or connected to an event (use true)
pfs-reason
:clinical-observation/pfs-reason
clinical-observation.event-reasononeThe reason (e.g. progression, censoring etc.) supplied for clinical observation PFS. Refers to entities in the :clinical-observation.event-reason namespace. See https://candel.parkerici.org/schema/#representing-data-for-survival-analysis-eg-pfs-os-etc for more information about modeling survival data
platelets
:clinical-observation/platelets
doubleonePlatelets, in x10E9/L.
potassium
:clinical-observation/potassium
doubleonePotassium, in mmol/L.
psa
:clinical-observation/psa
floatonePSA (Prostate-specific antigen) measurement from blood, in ng/mL
pt
:clinical-observation/pt
doubleoneProthrombin time, in sec.
rano
:clinical-observation/rano
clinical-observation.ranooneRANO (Response Assessment in Neuro-Oncology) assessment for brain tumor patients (MRI-based)
rbc
:clinical-observation/rbc
doubleoneRed blood cell count, in x10E12/L.
rdw
:clinical-observation/rdw
doubleoneRed cell distribution width, in %.
recist
:clinical-observation/recist
clinical-observation.recistoneThe RECIST (Response Evaluation Critera in Solid Tumors) score for this observation, refers to idents in the 'recist' namespace
recurrence
:clinical-observation/recurrence
booleanoneIndicates that the disease has recurred
sodium
:clinical-observation/sodium
doubleoneSodium, in mmol/L.
study-day
:clinical-observation/study-day
study-dayoneThe study-day at which this observation was performed
subject
:clinical-observation/subject
subjectoneThe subject that this clinical observation was performed in
timepoint
:clinical-observation/timepoint
timepointoneThe timepoint at which this observation was performed
total-bilirubin
:clinical-observation/total-bilirubin
doubleoneTotal Bilirubin, in mg/dL.
total-protein
:clinical-observation/total-protein
doubleoneTotal Protein, in g/dL.
tsh
:clinical-observation/tsh
doubleoneThyroid stimulating hormone, in mIU/L. Source feed writes this as mIU/L or mU/l; equivalent notations, normalised on import.
ttf
:clinical-observation/ttf
floatoneThe time to treatment failure of the subject in months. Such observations should be connected to the End of Study (EOS) timepoint
ttf-event
:clinical-observation/ttf-event
booleanoneIf TTF observation is censored (use false as the value) or connected to an event (use true)
ttf-reason
:clinical-observation/ttf-reason
clinical-observation.event-reasononeThe reason (e.g. progression, censoring etc.) supplied for clinical observation TTF. Refers to entities in the :clinical-observation.event-reason namespace. See https://candel.parkerici.org/schema/#representing-data-for-survival-analysis-eg-pfs-os-etc for more information about modeling survival data
tumor-sum-diam
:clinical-observation/tumor-sum-diam
floatoneThe sum of the tumor diameters in mm
tumor-sum-diam-perc-change
:clinical-observation/tumor-sum-diam-perc-change
floatoneThe percent change in the tumor sum of diameters. Must be a number in [-1 1]
uid
:clinical-observation/uid
[string …]oneunique identitySynthetic unique ID for clinical observation
wbc
:clinical-observation/wbc
doubleoneWhite blood cell count, in x10E9/L.

Referenced by